In other posts I write about about the 4E experiences Brian and I had at Gencon plus we had a practice 4E night one Sunday when Scott was absent.A simple generic map was printed, generic character sheets were provided, and an encounter or two ensued. Much of the night revolved around discussion of the game mechanic, how all of the new powers and features worked. This was to be expected – our group had skipped 3E completely and many of the new play features it provided, so going from 2E to 4E was a big jump.
Update (02/21/2010): I want to update item #7 from my list above:
7) Create initiative cards consisting of a 4X6 index card, one color for players and another for monsters. At the beginning of the encounter all initiative is rolled, documented on the cards, the cards are sorted, and thus initiative order is established for that encounter. Also included on the player initiative cards is "play data" information cut/pasted out of the players character sheet. These cards include the player and character names, their hit-points, attributes, defenses, and passive insight and perception. This character snapshot minimizes DM searching as needed.